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to unravel how plants control gene expression across different tissues and stress conditions by combining single-cell genomics, artificial intelligence, and synthetic biology. Apart from shedding light on
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and stress conditions by combining single-cell genomics, artificial intelligence, and synthetic biology. Apart from shedding light on the fundamental aspects of transcriptional control, this project
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developmental biology, cell biology and evolutionary biology. We like to implement novel omics technologies such as single cell approaches and chemical biology to help us answering our biological questions
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method, can engineer thousands of defined mutations in parallel in a single test tube in yeast. Strains are tagged by DNA barcodes, allowing to efficiently track mutations in cell populations during
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including fragmentomics, methylomics, etc). In addition, results will be compared and integrated with bulk and single-cell/spatial data obtained on matching tumor cells. About TOBI-lab The overarching goal
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project that combines cutting-edge approaches including state-of-the-art imaging techniques, pluripotent stem cell models, in vivo mouse models of neurological disorders, drug (brain) delivery and nanobody