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generate key structural and biophysical data to support the design of small molecule inhibitors with particular focus on protein production and crystallisation, solving protein-ligand structures, fragment
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practical knowledge of protein purification, ensemble biochemistry, and sample preparation to support your biophysical studies; • interact with biochemist and structural biology collaborators based
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describe and quantify the spatial characteristics and cellular interactions associated with colorectal response to neoadjuvant therapy.You will be jointly supervised by Professor Helen Byrne (Mathematical
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and structural biology of rhomboid-like membrane proteins. You should hold a PhD/DPhil in a topic relevant to structural biology and biochemistry, together with relevant experience. You should be able
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approaches, as well as being able to build on expertise in bacteriology, cell biology, structural biology and biochemistry in the group. You should hold, or be close to completion of, a PhD/DPhil in biological
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research projects require a creative, multidisciplinary approach, and as such provide opportunities across parasitology, structural biology, biochemistry and cell biology including single molecule
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the methodology and experimental approaches, as well as being able to build on expertise in bacteriology, cell biology, structural biology and biochemistry in the group. You should hold, or be close to completion
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including protein purification, SDS-PAGE, and western blotting. The post holder should be familiar with bioinformatics tools and databases (BLAST, protein structure prediction tools) and have basic
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spatially-resolved models of metastatic outgrowth in the liver which account for interactions between stromal, immune and tumour cells. You will analyse quantitative imaging data from a variety of sources
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), Neha Potnis (Auburn), Courtney Leisner (Virginia Tech)) and Thomas Lahaye (Tübingen)) to investigate the effect of fluctuating temperatures on the outcome and evolution of plant-pathogen interactions. We