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the next generation of scientists with the skills and knowledge to study complex biological processes that cannot be adequately understood within the limits of a single discipline. Projects and training
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includes research encompassing experimental and theoretical approaches at a wide variety of temporal and spatial scales, i.e. from molecules and microorganisms to patterns and processes occurring
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they continue to investigate. Approaches include genetics, spatial genomics, single-molecule biophysics, super-resolution imaging, computational modeling, and structural studies including X-ray
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contribute to the structure of filopodia and cell motility. The successful candidate will employ a broad range of biophysical and biochemical approaches, including site-directed mutagenesis, single-molecule
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into their molecular components in time and space, from single molecules to native tissue environments. The applicant is expected to have a strong computational focus on innovative development and application of novel
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. The project will involve the optimization of an experimental workflow, combining in vitro screenings, ex vivo tetramers staining, single-cell RNA sequencing and T cell receptor sequencing, to detect and
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. As part of the study, the candidate will receive training in single-molecule imaging. The applicant will also be expected to interact with graduate students in the laboratory and participate in
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, biochemistry, single molecule imaging, and we have enhanced these efforts using large-scale structure prediction using AlphaFold (predictomes.org). The Walter lab is a welcoming community where all members
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into active learning frameworks Explore automated dataset generation for molecules and materials Contribute to open-source tools for automated MLFF training Your profile Essential qualifications: Master's
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BBSRC Yorkshire Bioscience DLA Programme: The needle in the haystack - single molecule detection of extracellular vesicles in complex biological contexts School of Mathematical and Physical Sciences