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the direction of the Principal Investigator, assist in single-molecule biophysical analysis of force-producing enzymes. Among the key duties of this position are the following: Prepare samples and carry out
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biology – pioneering single-molecule techniques to investigate the mechanics and topology of fundamental DNA processes and theoretically modeling these processes using statistical mechanics and
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biology (cloning), Biochemistry - Advanced imaging (super-resolution, single-molecule imaging) - Advanced image analysis - Oral presentation, participation to meetings, writing of manuscripts The Institute
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for brain cancer and neurodegenerative diseases. Duties and Responsibilities: Design and develop small molecules, nucleic acids and peptide therapeutics. Design, prepare and characterize nanoparticles. Employ
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aims to develop physics-informed artificial intelligence tools for single-molecule fluorescence microscopy. The PhD student will focus on designing AI-based methods for quantitative analysis of protein
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, evo-devo, modelling of gene regulation, protein dynamics, signalling and metabolic pathways, computational morphodynamics, single molecule/cell imaging, systems or synthetic biology, and biophysics
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-metallic structures, one can direct and concentrate light at small enough volumes, to create nanoplasmonic cavities that can enclose even single molecules. Plasmons (or light in general) have the ability
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purifying small molecules; c) Experience in structural elucidation (1D and 2D NMR and MS); d) Experience in optimizing hit or lead compounds for single-target or multi-target applications; e) Experience in
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! The sensing technologies that are being developed in the Molecular Biosensing group (MBx, see www.tue.nl/mbx ) are unique in the world. The sensors are based on reversible single-molecule interactions
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metabolism. We are particularly interested in candidates with strong expertise in single molecule force spectroscopy and single molecule fluorescence spectroscopy to investigate genome biology processes