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Field
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regulation of polycystin-1 by the cleavage at the G-protein coupled receptor proteolysis site (GPS) motif, a key posttranslational modification of the protein, in cell signaling. The laboratory is highly
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for a broad range of cellular processes including lipid signaling, biological membranes, and energy metabolism; however, they are toxic to cells when present in excess. Dysregulation of fatty acid
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that activate kinases by removing phosphate groups, playing crucial roles in both physiological processes and various diseases. Developing drugs that target MKPs is challenging due to the nearly identical
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following skills: Strong interest in the field of neuroimaging, psychiatry and genetics. Computer skills: Strong level in the main informatics software (FSL, Freesurfer, fMRIprep) and coding languages (R
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understanding of the processes determing grasslands productivity, nutrient cycling and those leading to grassland soil degradation. • Experience in conducting experiments (field and laboratory). Experience
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | 3 days ago
-reviewed journals is required. Preferred Qualifications, Competencies, and Experience Candidates with previous experience in GPCR pharmacology, BRET/FRET assays, receptor signaling assays and/or protein
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | 3 days ago
for accelerated simulations of biomolecular recognition (such as drug binding and protein-protein interactions) and cellular signaling, and cutting-edge applications in drug discovery of critical targets including
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applications in python with PyTorch/Huggingface/SpaCy, applications of computer vision and signal processing in Tensorflow or PyTorch, Llama and GPT models. Essential Duties Develop and execute new and/or highly
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to control of infection. The focus of the project is on virus-specific CD8 T cells and the local hepatic regulation of their effector functions through environmental and cytokine-induced signals. The AG
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. Experience with total internal reflection fluorescence (TIRF) microscopy. Ability to perform image analysis and processing (e.g., ImageJ/Fiji) The following backgrounds are considered an asset or highly