15 structures "https:" "https:" "https:" "https:" "https:" "https:" "University of Southampton" positions at CEITEC MU
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) Where to apply Website https://www.ceitec.cz/postdoctoral-researcher-in-structural-virology/j659 Requirements Additional Information Work Location(s) Number of offers available1Company/InstituteCEITEC
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the CXCR4/SDF-1 axis. Blood. 2016 Sep 22;128(12):1609-13. doi: 10.1182/blood-2016-04-709519. Epub 2016 Aug 1. PMID: 27480113 Free PMC article Kipps et al. Chronic lymphocytic leukaemia. Nat Rev 2017 https
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to apply Website https://www.ceitec.eu/designing-coiled-coil-peptides-for-controlled-membrane-fu… Requirements Additional Information Work Location(s) Number of offers available1Company/InstituteCEITEC
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that induce fusion between lipid vesicles and endosomes. Using mesoscopic simulations, we will identify the key structural features of proteins with a transmembrane domain that promote membrane fusion
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finishing soon). international collaborations: University of Southampton, Univ.California- San Diego, Mayo Clinic, Dana-Farber Cancer Institute, EMBL, University of Turin (student internship available
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literature: Sandova V et al. IL4-STAT6 signaling induces CD20 in chronic lymphocytic leukemia and this axis is repressed by PI3K delta inhibitor idelalisib. Haematologica. 2021;106(11):2995-2999. https
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), which establishes and maintains transcriptionally silent chromatin states. This PhD project aims to investigate how structural and biochemical features of these Polycomb proteins determine their
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of leukemias, including chronic lymphocytic leukemia (CLL) and other B-cell malignancies. Much evidence from the latest research shows that CLL cells have an extra deregulated chromatin structure and show an
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regulators and non-coding RNAs. Semin Oncol. 2018 Oct;45(5-6):291-30 https://pubmed.ncbi.nlm.nih.gov/30360879/ Zeni and Mraz LncRNAs in adaptive immunity: role in physiological and pathological conditions. RNA
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investigator of 4 grants (AZV 3x, NPO, in the past ERC Starting grant). Dr. Mraz has currently 7 PhD students, with 3 finishing soon). international collaborations: University of Southampton, Univ.California