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candidate profile: Must-have: A PhD degree or equivalent in virology, structural biology, biochemistry, molecular biology or related field Expertise in cryo-EM, cryo-ET, or X-ray crystallography is an
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. 2012; 24(6):634-9. https://pubmed.ncbi.nlm.nih.gov/22960555/ Research area: Cancer biology Keywords:CLL, microenvironment, CD20, BTK/PI3K inhibitors Funding for the PhD candidate: In the academic year
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the CXCR4/SDF-1 axis. Blood. 2016 Sep 22;128(12):1609-13. doi: 10.1182/blood-2016-04-709519. Epub 2016 Aug 1. PMID: 27480113 Free PMC article Kipps et al. Chronic lymphocytic leukaemia. Nat Rev 2017 https
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targets for therapy. Recommended literature: Zeni and Mraz LncRNAs in adaptive immunity: role in physiological and pathological conditions. RNA Biol. 2021 May;18(5):619-632. https://pubmed.ncbi.nlm.nih.gov
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Supervisor: prof. RNDr. Robert Vácha, PhD. Topic title: Designing Coiled-Coil Peptides for Controlled Membrane Fusion and Intracellular Delivery Annotation: Most approved drugs act on cell-surface targets
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Supervisor: prof. RNDr. Robert Vácha, PhD. Topic title: Overcoming the Endosomal Barrier: Design Principles of Fusogenic Proteins for Lipid Vesicles Annotation: Cancer remains one of the leading causes
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practices. The ideal researcher (EU Researcher Profile: R2) profile: Must-have: A PhD degree or equivalent in structural biology, Chemistry, biochemistry, biophysics, or a related field. Expertise in
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), which establishes and maintains transcriptionally silent chromatin states. This PhD project aims to investigate how structural and biochemical features of these Polycomb proteins determine their