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and biophysics. Develop computational pipelines integrating ASR, structure prediction, and energetic analysis. Apply and/or develop ML/AI methods for protein design and evolutionary inference. Analyze
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of chloroplast proteins contributes to immune responses in plants and crops. Protease- and substrate-centered proteomics will be performed in close collaboration with the SciLife lab for Chemical Proteomics
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purifying proteins from bacterial expression systems. -Participating in quantitative interactomics experiments and data analysis. -Development of cellular assays to validate interactions Required
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, metabolic enzymes). Experience with developing protein binders (e.g. nanobodies). Experience with molecular dynamics simulations. Strong quantitative assay development/analysis skills; experience bridging
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“pan-terminome” knowledge base of plant proteoforms and to uncover how conserved proteolytic processing of chloroplast proteins contributes to immune responses in plants and crops. Protease- and
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About the project Systemic amyloidosis comprises severe protein misfolding diseases in which amyloid fibrils accumulate across multiple organs, leading to progressive dysfunction. AL (light‑chain
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, physics and materials science. Scientists with expertise in biophysical methods of interaction analysis are responsible for a facility belonging to SciLifeLab, part of a national infrastructure for research
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fellow's work involves evaluating the role of CLDN1 in the growth of xenograft tumors and determining how CLDN1 modulates the tumor microenvironment. The transmembrane protein CLDN1 plays an important role
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, crystallography, structural biology Principal Investigator: dr hab. Agnieszka Kiliszek Research topic: A comprehensive structural and functional analysis of toxic RNA-protein interactions for better
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experiments will include protein purification, enzymatic and biophysical characterization, and evaluation of their effects on microbes, including in field experiments. Other work could relate to research