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biological scales. Project background Cells are mechanically heterogeneous systems composed of proteins, membranes, and compartments with distinct physical properties. In parallel, they continuously sense and
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identified previously unrecognized cell-intrinsic mechanisms that regulate replisome dynamics and fork speed, establishing replisome velocity control as a key genome surveillance strategy (PMIDs: 29123070
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and molecular mechanisms underlying phenotypic variability in quiescent cell populations and their impact on adaptation, antifungal resistance, and population dynamics. The successful candidate will
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in person in São Paulo and involves single-cell and spatial transcriptomics analysis, integration of multi-disease datasets, investigation of cell–cell communication, and the development
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from the lab has identified previously unrecognized cell-intrinsic mechanisms that regulate replisome dynamics and fork speed, establishing replisome velocity control as a key genome surveillance
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will continue to investigate human brain development with a focus on stem cell lineages and synaptic diversity. See https://scholar.google.com/citations?user=09RosEoAAAAJ (link is external) for a
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postdoctoral position within the ERC-2024-STG-funded project 1101165141-MANAGE HSC. This project combines stem cell and stem cell niche biology, bone marrow/niche engineering, and cell mechanics to investigate
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layers during the wet/dry cycles induced by the fuel cell operation. Conversely, strong mechanical interfaces will lead to completely bonded layers. While numerous studies are available on the effect
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are lacking. The project In this postdoctoral research project, you will chart the molecular and cellular mechanisms active in the airway wall of patients with severe asthma. You will compare these cell-type
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) plays a critical role in driving tumor aggressiveness and influencing treatment responses. Key players within this microenvironment are cancer- associated fibroblasts, endothelial cells, immune cells and