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heterodimer (Nucleic Acids Res 50:3254, 2022); revealed a mechanism that expands PXR's ligand binding pocket to reduce ligand's binding affinity (Proc Natl Acad Sci U S A. 120: e2217804120, 2023); and
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pocket to reduce ligand's binding affinity ( Proc Natl Acad Sci U S A . 120: e2217804120, 2023 ); and discovered the first CYP3A5-selective inhibitor and its structural basis ( J Am Chem Soc 143:18467
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