-
methods for single-cell data analysis (tools developed by the team : https://github.com/cantinilab ). Single-cell high-throughput sequencing, extracting huge amounts molecular data from a cell, is creating
-
crosstalk with tumor cells, immune cells and the vasculature. We perform mostly in vivo studies, combining lineage tracing and depletion models, flow cytometry, confocal microscopy and unbiased approaches
-
Host Lab our lab (https://research.pasteur.fr/en/team/cellular-plasticity-in-age-related-pathologies/ ) explores how cellular senescenceorchestrates tissue repair and regeneration. We focus on how
-
models, flow cytometry, confocal microscopy and unbiased approaches such as single cells transcriptomics, spatial transcriptomics and epigenetics to characterize molecular and cellular mechanisms. Using
-
proximity labeling is expected. Experience in confocal imaging and/or super-resolution microscopy would be a plus. The proposed research will be supervised by Dr Marie Prevost (https://research.pasteur.fr/en
-
expertise in immunology or cell biology, with solid experimental lab skills. – Experience with animal models (mouse work) and advanced immunological techniques. – Skills in RNAseq analysis (highly valued
-
. Measuring and predicting the effect of copy number variants on general intelligence in community-based samples. JAMA Psychiatry 2018 75(5):447-457. Mercati O. et al. CNTN6 mutations are risk factors for