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Shiga-toxin encoding E. coli (STEC) are of great public health concern due to the risk of foodborne gastroenteritis progressing to the clinically severe haemolytic uraemic syndrome (HUS). Toxin
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% of the pregnant cohort can develop pyelonephritis compared to 2% of non-pregnant counterparts. Uropathogenic E. coli (UPEC) is found in over 40% of cases and is the most important cause of RUTIs. There are various
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permeability of the gut epithelium and overactive immune response. Notably, a particular type of E. coli which adheres to and invades intestinal epithelial cells (AIEC), is highly prevalent in CD tissue, but it
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for engineering synthetic gene circuits to program temporal tasks in E. coli cells. This position is funded by an ERC Starting Grant (project: TICK-TOCK Do and Die). Past achievements of Dr. Santos-Moreno include
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PhD Project in the development of a synthetic biology platform for efficient production of disulfide-rich proteins in E. coli Department of Biology Faculty of Science University of Copenhagen
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of markers• Task 5.1: Perform traditional indicator of contamination assays (e.g., E. coli).• Task 5.2: Quantify novel genetic viral and fungi markers identified in task 3.• Task 5.3: Conduct NGS/metagenomic
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the drivers and evolutionary factors influencing AMR in Brazil in pigs and examine a wider set of bacterial species, including Salmonella, E. coli and other bacterial pathogens identified through
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quality control of viral vectors using methods such as qPCR Experience in cloning, protein expression in E. coli, and purification Experience in analytical methods including SDS Page, Western blot, ELISA In
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-antibodies display a series of remarkable properties including high stability and solubility, easy production in E. coli, easy modification by genetic engineering, high tissue penetration and an ability