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crystallography, cryo-electron microscopy Research topic: Structural and functional studies of plant transcription factors Principal Investigator: Marta Grzechowiak, PhD I. Project description: Are you interested
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. Stockholm University has a long tradition in the development of techniques for electron crystallography to achieve new structural insights. This project focuses on the structural investigation and synthesis
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in any of the following methods will be advantageous: Single-crystal crystallography, Powder X-ray diffraction, NMR, UV-vis, IR and Luminescence spectroscopy, electrochemistry. The candidate will hold
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effects of charge transfer (for example in cryptochrome and photolyase proteins) using time-resolved serial femtosecond crystallography at Free-electron laser sources. The project requires production and
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integrative structural biology studies: (https://www.i2bc.paris-saclay.fr/facilities/ ). In particular, the doctoral student will have access to cryoEM instruments (Glacios at the I2BC and Titan Krios
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Andrew Lovering X-ray crystallography. Thus, overall once completed, we envisage the PhD student will have an excellent all-around knowledge in structural biology and have the ability to apply native mass
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, biochemistry, AlphaFold and structural characterisation by X-ray crystallography and cEM. Firstly, this will provide insights into new regulatory mechanisms relevant to several fundamental signalling pathways
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to track structural changes in proteins as they work. More information about the research group is found at: https://cmb.gu.se/english/about_us/staff/?languageId=100001&disableRedirect=true&returnUrl=http%3A
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at the host-virus interface. Our central methodologies are solution NMR, crystallography and SAXS, together with a broad method spectrum from biochemistry and biophysics. In this project, we plan to analyze
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mitochondrial physiology and disease. Candidates should hold a Ph.D. in biophysics, structural biology, or a related field, and have experience in protein purification, crystallography, cryo-EM, or membrane