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The Centre for Doctoral Training in Nanoscience and Nanotechnology (NanoDTC) at the University of Cambridge invites applications for its 3.5-year interdisciplinary PhD programme. The programme
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non-clinical PhD studentship in cardiometabolic research, commencing October 2026 in the Department of Medicine (VPD Heart & Lung Research Institute), University of Cambridge. The project will be based
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mouse models and immunology expertise (CRUK-CI), access to relevant patient material (matched fresh-frozen PDAC and serum samples). We will utilize AstraZeneca expertise in spatial and circulatory
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processes associated with CIN [1], leveraging single-cell DNA sequencing understand CIN heterogeneity [2], and development and implementation of machine learning and AI models to imaging data [3]. The student
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tumours and metastases with the goal to design combinatorial therapeutic approaches. The project will involve the use of genetically complex organoid-derived transplantation mouse models of pancreatic
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computational modelling to be used to design and re-engineer flower architecture. The RA's main focus will be on computational modelling of gene regulatory networks for predicting the mechanisms leading
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on cell viability and DDR activation in established human cell models. The student will perform CRISPR screens to determine factors that affect resistance/sensitivity and follow these up with mechanistic
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chromatin profiling methods along with CRISPR/Cas9-meduated cell line engineering and various animal models. You will study the effects of the activation or depletion of chromatin-modifying enzymes using
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prostate cancer risk across diverse ethnic groups. This work aims to support more equitable risk stratification in cancer screening programmes. Using simulations based on multistate modelling framework
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comprehensive model of what tranquillity is, the factors that influence it and how to design for it. Attention to design contexts and design processes will be key to ensuring that useful measurements, methods and