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Chemistry and Chemical Biology. The project will combine the advances in Antibody-drug conjugates (ADCs) with antisense oligonucleotides. ADCs have revolutionized targeted cancer therapy by delivering
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both chemistry and biology to explore fundamental mechanisms of genome function (http://www.balasubramanian.co.uk ). Our projects involve developing and using cutting edge technologies in chemical
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to optimise built-environment thermodynamics and occupant comfort by creating predictive AI tools for spatiotemporal heat transfer. Machine learning algorithms will identify energy inefficiencies and propose
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high dynamic range (HDR) imaging is redefining the way smartphone cameras and displays capture the world. Despite HDR becoming the new standard, many classic image-processing algorithms and generative
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or a related, relevant subject. Familiarity with molecular and chemical biology techniques and specific skills in assay development, enzyme kinetics, DNA library generation, structural biology, organic
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algorithms will turn these high-resolution insights into searchable, verifiable databases, seeking to better inform assay decision making. Applicants should have (or expect to be awarded) a good UK Master's
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details Our lab exploits both chemistry and biology to address fundamental mechanisms of genome function. While many genetic determinants of cancer are known, alternative nucleic acid secondary structures
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to cancer biology, as well as a strong commitment of developing and using new tools to address cutting-edge questions in these fields. This studentship is embedded within the piRNA team, consisting of both
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screens. Nature Reviews Molecular and Cell Biology 2023. 24, 477-494. Awwad, S.W., Doyle, C., Coulthard, J., Bader, A.S., Gueorguieva, N., Lam, S., Gupta, V., Belotserkovskaya, R., Tran, T-A
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technologies, bulk and single-cell RNA-sequencing, flow cytometry, multiplex immunofluorescence, and standard molecular biology and biochemistry techniques. A computational component may also be available