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. This project will use large-scale metagenomic mining to uncover novel phage-host associations and identify phage-encoded enzymes, such as endolysins, with antibacterial activity. By integrating evolutionary
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the synergistic effects of monoclonal antibodies and colistin. Building on extensive preliminary data, the project aims to uncover the mechanisms behind this synergy using advanced biophysical and molecular
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learning and machine learning for biological data Sequence and structure analysis of large-scale datasets Functional annotation and evolutionary analysis Collaborative research with experimental virology
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culture and in vitro models of mucosal immunity Data analysis using Python and digital image processing These skills are highly transferable to careers in biomedical research, pharmaceutical development
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Develop an active learning-driven platform for compound selection and optimisation Integrate robotic sample preparation, automated data acquisition, and computational analysis Advance five existing
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Supervisors: Prof Stavroula Balabani Prof Panagiota Angeli Abstract: Oral biofilms are a major cause of dental and periodontal diseases, including endodontic infections and dental caries the most prevalent noncommunicable disease globally. The confined and complex architecture of the oral...
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disinfectants. With antimicrobial resistance (AMR) on the rise, there is an urgent need for non-antibiotic strategies to prevent and control biofilm formation on medical devices. This PhD project proposes a novel
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Supervisors: Prof Manish Tiwari Prof Shervanthi Homer-Vanniasinkam Clinical Partner: The Royal National Orthopaedic Hospital (RNOH) Collaborator: Dr. Priya Mandal – UCL Mechanical Engineering Abstract: Medical device-associated infections (MDAIs) are a major clinical and economic burden,...
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cultivation and molecular cloning Quantitative data analysis and process optimisation Synthetic and molecular biology techniques Research design, interdisciplinary collaboration, and scientific communication
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PhD Studentship: Nanopore Technology for Rapid and Accurate Measurement of Antibiotic Concentrations
environments. Training and Student Development: The student will gain hands-on experience in: Molecular biology and aptamer engineering Nanopore fabrication and single-molecule sensing Data acquisition and