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since its discovery 150 years ago, due to a lack of model species 2,3. The candidate will use a combination of genetic tools to identify the molecular machinery responsible for chromosome fragmentation in
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the development and activity of human beige adipose tissue. We will use a human beige adipose tissue organoid model recently developed by the team from cells derived from the vascular stromal fraction of human
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software and models will be developed for data processing and analysis. Finally, the instrument capabilities will be evaluated using protocols and reference samples previously developed for this purpose in
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