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. The second analyzes a non-canonical function of the mitochondrial enzyme Co-enzyme Q6 in regulating the cellular balance between OXPHOS and glycolysis in response to inflammation. We have substantial
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laboratory to elucidate the effect of Abeta42 on mitochondrial liquid-liquid phase separation using live-imaging techniques. Research activities will focus on: (1) Molecular mechanism of amyotrophic lateral
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mutations, mitochondrial dysfunction and chronic inflammation intersect to contribute to clinical and pathological heterogeneity in PD. The successful candidate will work at the interface of basic and
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dynamic group investigating mitochondrial genetics and function using Drosophila as the model (http://themalab.co.uk ). The candidate will use genetic and biochemical approaches to study mitochondrial DNA
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the analysis of senescent markers, mitochondrial dysfunction and transcriptional deregulation of target genes. V - Initial grant duration: 6 months V.I - Renewal Possibility: Non-renewable VI - Funding and
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Biochemistry Research Assistants 01 Department's Website: Summary of Job Duties: The Postdoctoral Fellow will conduct independent and collaborative research on mitochondrial membrane proteins. The position
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the molecular basis of sex differences in cardiac metabolism and mitochondrial biology, both in health and disease. Our work focuses on the role of sex chromosomes, whose contribution remains largely unexplored
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the work being pursued in the laboratory, prospective applicants can refer to the following papers: 1. K.O. Tan et al., MAP-1 is a mitochondrial effector of Bax, (Track II), Proc. Natl. Acad. Sci. USA