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The post holder will design and synthesise small molecules aimed at developing new therapeutic strategies for ASS1-deficient tumours. Your work will develop important structure–activity relationship (SAR
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). Based at Seagate Technology (Springtown), you will lead microfabrication and metrology to realise device structures from pre-deposited magnetic wafers, including design and patterning of pillars and Hall
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reporters; advanced imaging and quantitative phenotyping to resolve root structure and cellular responses at high spatial resolution; and transcriptomic and chromatin-based approaches to identify regulatory
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is trial protocols—including patient identification, recruitment, and performing trial visits—the role is structured to provide an unparalleled training environment. You will join one of the world’s
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enzymes, SleB. Bacterial spores are among the most pernicious cells in nature. Formed as survival structures in response to nutrient starvation, their ubiquity and extreme resistance to heat and other
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, XRF, isotopic, and tephra analysis, alongside the construction of Bayesian age–depth models using radiocarbon, 210Pb, and tephrochronology. Candidates with experience in metagenomics (sedimentary aDNA
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economists based in Population Health Sciences in Bristol Medical School. This post is funded by a Wellcome Trust Discovery Award focussed on improving our understanding of the global impact of structural
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important structure–activity relationship (SAR) data across a number of different tumor types. The ultimate aim is to derive a number of lead compounds to take forward to advanced in vitro and in vivo studies
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University College London. This ambitious programme addresses the sustainability challenges of engineering plastics in the transport, electronics, and construction sectors. It investigates a wide range of
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assurance/insurance frameworks, including algorithmic insurance contracts, parametric insurance structures, and data-driven risk quantification methods (e.g., conformal prediction and inverse conformal