PhD Position in Hydrogen/Deuterium Exchange Mass Spectrometry to Study the Regulation of Lipoprot...
Do you want to join one of the strongest biomedical mass spectrometry research environments in Europe? Here is an excellent opportunity to work on an exciting and challenging project in such an environment.
The Jørgensen group at the Protein Research Group /Section for Biomedical Mass Spectrometry at the Department of Biochemistry and Molecular Biology (BMB) at the University of Southern Denmark (SDU) is looking for a highly motivated PhD student to join a project on elucidating the mechanisms by which endogenous activators and inhibitors regulate lipoprotein lipase using hydrogen deuterium exchange mass spectrometry (HDX-MS).
This is a highly interdisciplinary project with nine investigators with expertise in different research fields working in six institutions in six countries. You will be part of an international and dynamic research team. You will be motivated to use advanced HDX-MS to investigate the regulation of lipoprotein lipase. You will manage an independent research project and assist in the supervision of undergraduate students.
The Jørgensen group is part of the Protein Research Group /Section for Biomedical Mass Spectrometry at BMB and offers a strong international research environment in proteomics, protein chemistry, biomolecular mass spectrometry, and computational proteomics.
Qualifications
We are looking for a highly motivated and enthusiastic candidate with excellent communication skills.
For consideration, applicants must have:
- A recent Master’s degree in biochemistry, protein science/proteomics, analytical biochemistry or a related field
- Experience in experimental protein biochemistry and mass spectrometry
- Excellent English speaking, reading and writing skills
In addition, applicants with practical experience with HDX-MS and/or LC-MS/MS will be preferred.
A recent publication of ours on lipoprotein lipase studied by HDX-MS is: Kumari et al., ANGPTL3/8 is an atypical unfoldase that regulates intravascular lipolysis by catalyzing unfolding of lipoprotein lipase. Proc. Natl. Acad. Sci. U.S.A., 122, e2420721122 (2025)
Place of work: Protein Research Group (Assoc. Prof. Thomas J.D. Jørgensen), Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark
Application deadline: July 1, 2025 at 23:59 hours local Danish time.
Please see the full call, including how to apply, on www.sdu.dk