3 structures "https:" "https:" "https:" "https:" "https:" "https:" "https:" "https:" "https:" positions at Institute of Molecular Genetics of the Czech Academy of Sciences in Czech
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to elucidate the molecular and cellular mechanisms of plectin inhibition using plecstatin, a first-in-class high-affinity plectin inhibitor. The project combines structural characterization with functional
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tissue culture experiments and basic molecular biology techniques (PCR, plasmid construction) as well as basic microscopic skills. The candidate should be able to work with scientific literature and
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, Honigmann A, Pigino G: The molecular structure of mammalian primary cilia revealed by cryo-electron tomography. Nat Struct Mol Biol 2020 27(12):1115-1124. Binó L, Mikulenková E, Štepánek L, Bernatík O
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