Sort by
Refine Your Search
-
Category
-
Program
-
Field
-
involved in pathobiological processes and the development of genetic instability-driven conditions, rendering them a fascinating subject within structural biology. This project will integrate ¹⁹F NMR and
-
receptor (BCR) signaling and B-T cell interactions. Human genome contains large numbers of lncRNAs that can regulate various physiological cellular processes or contribute to the onset or aggressiveness
-
processivity of RNA Polymerase IIat core DNA replication genes. Apart from the C-terminal domain of RNA Polymerase II, other cellular substrates of CDK12 are not known. In this research, we propose using a
-
literature: Sandova V et al. IL4-STAT6 signaling induces CD20 in chronic lymphocytic leukemia and this axis is repressed by PI3K delta inhibitor idelalisib. Haematologica. 2021;106(11):2995-2999. https
-
. Annotation: Protein-DNA interactions are critical in cellular processes and genetic instability-related conditions, particularly involving G-quadruplexes (G4) and their complementary C-rich sequences (i-Motif
-
references: 1) A. Sasukimar et al. Supramolecular covalency of halogen bonds revealed by NMR contact shifts in paramagnetic cocrystals. Chem. Sci. 2025, 16, 20239-20244. https://doi.org/10.1039/D5SC05769H . 2
-
the CXCR4/SDF-1 axis. Blood. 2016 Sep 22;128(12):1609-13. doi: 10.1182/blood-2016-04-709519. Epub 2016 Aug 1. PMID: 27480113 Free PMC article Kipps et al. Chronic lymphocytic leukaemia. Nat Rev 2017 https
-
literature: Beekman et al. The reference epigenome and regulatory landscape of chronic lymphocytic leukemia. Nature Medicine 2018 https://pubmed.ncbi.nlm.nih.gov/29785028/ Sun et al. The immune
-
regulators and non-coding RNAs. Semin Oncol. 2018 Oct;45(5-6):291-30 https://pubmed.ncbi.nlm.nih.gov/30360879/ Zeni and Mraz LncRNAs in adaptive immunity: role in physiological and pathological conditions. RNA
-
Axis Regulates Homing Capacity and Tonic AKT Activity in Chronic Lymphocytic Leukemia. Blood 2021 March (epub). https://pubmed.ncbi.nlm.nih.gov/33786575/ Pavlasova G, et al…. Mraz M. Ibrutinib inhibits