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to elucidate the molecular and cellular mechanisms of plectin inhibition using plecstatin, a first-in-class high-affinity plectin inhibitor. The project combines structural characterization with functional
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: https://ecrin.org/ , https://creatic.muni.cz/ The scope of your work will be: Providing expert consultation to research teams in the planning and implementation of international clinical trials
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, Honigmann A, Pigino G: The molecular structure of mammalian primary cilia revealed by cryo-electron tomography. Nat Struct Mol Biol 2020 27(12):1115-1124. Binó L, Mikulenková E, Štepánek L, Bernatík O
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tissue culture experiments and basic molecular biology techniques (PCR, plasmid construction) as well as basic microscopic skills. The candidate should be able to work with scientific literature and
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find out more about us on our websites: https://ecrin.org/ , https://creatic.muni.cz/ The scope of your work will be: Providing expert consultation to research teams in the planning and implementation
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with data, and present conclusions in a comprehensible manner. Teaching and facilitation skills, ability to structure teaching and provide constructive feedback. Independence, reliability, good
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, wood processing technologies, and the construction of wooden buildings in its academic and research activities. Its work encompasses all areas related to the processing and use of wood, from traditional
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the individual and institutional levels and provide an excellent environment for students and staff. You can find out more about us on our website https://www.law.muni.cz/content/en/ , on Facebook or on the MU
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NMR spectroscopy has emerged as a unique and powerful approach for probing biomolecular structure, dynamics, and interactions directly within living human cells under near-physiological conditions. It
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of these structures, thereby mediating replication, repair, transcription, and DNA damage response through protein barriers. Peptides from helicase motifs can be used to investigate atomistic details of G4-Helicase