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for Molecular Neurology are recruiting a postdoctoral researcher to establish next-generation humanized and engraftment models for studying peripheral neuroimmune mechanisms driving Parkinson’s disease. Building
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and technicians and develop an independent research profile Access to state-of-the-art infrastructure A stimulating, diverse international world-class research environment Animal models, expertise in
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to join our team. We are an international and multidisciplinary team, integrating research from genetics, epigenetics, transcriptomics, proteomics, biomarker research, and cell models. Our lab is at
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training data. You will unravel the cis-regulatory code controlling context-dependent gene expression and use this information to design synthetic promoters. You will train and evaluate predictive models in
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are seeking a motivated and enthusiastic colleague with strong computational skills in the analyses of complex data sets to join our teams. About the project We have generated advanced brain on chip models
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intervention trials (e.g., diet, FMT), and ex vivo gut models enabling advanced multi-omics analyses of these samples. In addition the lab also maintains a large culture collection, partially linked to genomic
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critical roles of ion channels—particularly the TRP superfamily—in physiological and pathological processes. Our interdisciplinary approach spans from foundational electrophysiology to translational models
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-scale screens to study fundamental principles in molecular and complex trait genetics using microbes as model systems. Our core technology MAGESTIC (https://doi.org/10.1038/nbt.4137 ), a CRISPR/Cas9-based
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the fundamental aspects of transcriptional control, this project also opens new avenues for the design of climate-resilient crops. Supported by single-cell profiling and predictive artificial intelligence models
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question: « what makes our brain human ? » (Vanderhaeghen and Polleux, Nat. Rev. Neurosci. 2023). We combine cutting-edge approaches such as pluripotent stem cell models of human corticogenesis, human-mouse