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, and dysregulation of R-loop processing is associated with cancer and neurodegenerative diseases. We have developed an unbiased mass spectrometry-based proteomics approach to identify proteins
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: Nuclear mRNA export is an essential step in eukaryotic gene expression, ensuring that mature transcripts are delivered from the nucleus to the cytoplasm for translation. Multiple challenges are faced in
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associated with cancer and neurodegenerative diseases. We have developed an unbiased mass spectrometry-based proteomics approach to identify proteins that regulate R-loops in human cells and discovered a role
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step in eukaryotic gene expression, ensuring that mature transcripts are delivered from the nucleus to the cytoplasm for translation. Multiple challenges are faced in this process: How are mRNAs
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in vivo and in vitro approaches to study maternal mRNA regulation across multiple levels. Zebrafish is our primary in vivo model, offering powerful genetic tools and abundant embryos for applications
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. g. single cell sequencing and proteomic). Theoretical and practical knowledge in molecular and cell biology and/or protein chemistry are expected for successful candidates. The candidate should have
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proteomic). Theoretical and practical knowledge in molecular and cell biology and/or protein chemistry are expected for successful candidates. The candidate should have an interest in systems biology
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strong core facilities that offer state-of-the-art equipment and training in protein production, microscopy, proteomics, cytometry, genomics and bioinformatics. Activities and responsibilities
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strong core facilities that offer state-of-the-art equipment and training in protein production, microscopy, proteomics, cytometry, genomics and bioinformatics. Activities and responsibilities R-loops
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Max Planck Institute of Immunobiology and Epigenetics • | Freiburg im Breisgau, Baden W rttemberg | Germany | about 21 hours ago
epigenetics, biophysics, metabolism, biochemistry, cell biology, proteomics, bioinformatics and functional genomics. We train doctoral researchers to become self-reliant and to acquire and utilise the knowledge