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purifying proteins from bacterial expression systems. -Participating in quantitative interactomics experiments and data analysis. -Development of cellular assays to validate interactions Required
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are important modifiable factors that influence metabolic processes and the gut microbiota. Current recommendations advocate for an adapted diet, with a reduction in animal proteins in favor of plant-based
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, metabolic enzymes). Experience with developing protein binders (e.g. nanobodies). Experience with molecular dynamics simulations. Strong quantitative assay development/analysis skills; experience bridging
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Center for Biologics Evaluation and Research (CBER) | Silver Spring, Maryland | United States | about 20 hours ago
of synonymous variants in therapeutic proteins using integrated computational and experimental approaches. A central component of the project involves applying and developing advanced bioinformatic tools to model
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“pan-terminome” knowledge base of plant proteoforms and to uncover how conserved proteolytic processing of chloroplast proteins contributes to immune responses in plants and crops. Protease- and
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for plant transformation, discovering protein-protein interactions using proximity labeling, reverse genetics - preparation of mutants by CRISPR/Cas9 systems, phenotypic analysis of mutants using mainly
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About the project Systemic amyloidosis comprises severe protein misfolding diseases in which amyloid fibrils accumulate across multiple organs, leading to progressive dysfunction. AL (light‑chain
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Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description Protein pea is cultivated for the high nutritional value of its
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: This project will investigate the nuclear function of TPL-2 kinase. Techniques: Cell culture, protein-protein interaction studies, CRISPR/Cas9 gene editing, transcriptomic analysis by QPCR and RNA-seq
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biology platform https://www.scilifelab.se/units/structural-proteomics/ The unit provides access to cutting-edge equipment and expertise, for the analysis of protein interactions and conformational dynamics