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surrounding nascent AQP chains changes during synthesis. Proteomic analysis will identify potential interactors with translation machinery, chaperone proteins or quality control factors during AQP biogenesis
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based on the Aston Campus in Birmingham, UK. Background Membrane proteins are vital for cellular function and serve as key drug targets. Despite their importance, our knowledge of their biogenesis
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develop a strong and transferrable skillset in cell culture/protein expression, NMR spectroscopy, data analysis and food science. You will also have the opportunity to undertake a placement at PepsiCo. Mode
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/or high-quality publications and/or substantial contributions to advanced research programmes Extensive experience with experimental model systems and DNA and protein-based assay methods including PCR
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causal component of Alzheimer’s Disease (AD). Brain immune response is associated with the accumulation of both tau and amyloid proteins and is implicated in neuropathogenesis and multiple chronic
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prodromic stage of PD. Despite this, the mechanism underlying PD-related cardiac ANS degeneration is unknown. The Ala30Pro (A30P) missense mutation in the alpha-synuclein protein is a genetic risk factor of
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or surface plasmon resonance), mass spectrometry, analysis of protein structures or enzymology • Be able to demonstrate a high level of expertise and success in the previous research areas, e.g. by
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can be altered by the dietary addition of plant-based compounds such as tannins, flavonoids or essential oils (Bature et al., 2024). In a recent meta-analysis Belanche et al. (2020) reported
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metabolism. Our lab focuses on understanding the biology of inflammasomes - proteins that regulate processes during infection and inflammation. You will work on exciting projects exploring how lipids in cells
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Department: Chemistry Title: Combinatorial Discovery of Peptide Materials as Ice Binding Protein Mimics Application deadline: All year round Research theme: Chemical Biology, Materials Chemistry