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Field
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microscopy and nanomanipulation techniques to record the live construction of such a virus, at the nanoscale. By unveiling how viruses are built up, we will not only provide fundamental understanding
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is the covalent attachment of lipids to proteins, regulating their trafficking, protein–protein interactions, and stability. This post-translational modification is dynamically controlled by families
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enzyme engineering. The PhD project will involve bioinformatic selection of candidate enzymes, employing a combination of ‘off-the-shelf’ tools based on both sequence and structure. These enzymes will be
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construction of such a virus, at the nanoscale. By unveiling how viruses are built up, we will not only provide fundamental understanding of these disease causing agents, we will also be able to better
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and reporting of data and results. Communicate and interact with the research group, as well as with collaboration partners from academia and industry. Write scientific publications and present
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approach, models and programs. And you enjoy interacting with and coaching talented bachelor and master students, while expanding your own knowledge and competencies. You also have: An MSc degree in Applied
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of your approach, models and programs. And you enjoy interacting with and coaching talented bachelor and master students, while expanding your own knowledge and competencies. You also have: An MSc degree in
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interact with the group of Javier Alonso-Mora as part of the FlexMobility project as there will be in total 2 PhDs and 1 postdoctoral researcher working in a collaborative way to reach the goal of designing
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of ‘off-the-shelf’ tools based on both sequence and structure. These enzymes will be produced, screened and the best variants subject to protein engineering campaigns. Once highly active variants
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the mechanical properties and structure of SAC films; study the structure-function properties of SAC films; elucidate key mechanisms of SAC-biofilm interactions; translate the insights into potential guidelines