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analysis of data coming out of a prototype calibration system which has been deployed in Super-K. The sensitivity of Hyper-K to supernovae is also under study. Students are expected to spend up to 12 months
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for downhole milling tools. Conduct Finite Element Analysis (FEA) of cutting mechanics under downhole conditions. Support design and validation of prototype tools using the company’s bespoke instrumented test
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A search for pharmacological inhibitors of a cancer-associated adhesion GPCR in the zebrafish embryo
, chemoinformatics and image analysis). The student will gain experience in working with zebrafish embryos, and the use of high-content imaging techniques (fluorescent in situ hybridisation, immunohistochemistry
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of the produced EVs using high resolution cell imaging. You will investigate the mechanism(s) of any EV-related chemotherapy resistance observed. Finally, you will attempt to target EV production (by CRISPR Cas9
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proteomics approaches and a variety of imaging techniques, including high-throughput, confocal and live cell imaging. Please apply for this project using this link: https://www.sheffield.ac.uk/postgraduate/phd
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secretion from chromaffin cells. Using a combination of patch clamp electrophysiology and live cell fluorescent imaging the interactions between heterotrimeric G protein subunits, their effectors and the
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neurons. Using a combination of high resolution live cell fluorescent imaging, electrochemistry and patch clamp electrophysiology, we recently discovered that activation of GLP-1Rs promotes the formation
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for sustainable aviation fuels supply chain. The dual effects of sustainability and security of energy and critical materials supply will underpin the model development. It will involve a paradigm shift which
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instructions for maintenance works to be carried out in a timely, cost efficient manner by either University staff or external contractors, ensuring works comply with current legislation, Health & Safety codes
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. You will have diverse skill-set, good organisational skills, the ability to research, problem solve and implement ideas in a hands-on environment. Whilst having a practical approach, a positive attitude