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Cambridge Institute (CRUK CI), to investigate the molecular mechanisms of small RNA-mediated chromatin silencing. As a whole, the Hannon laboratory has broad interests that range from discovery research
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: Advanced molecular and protein analysis Mass spectrometry-based imaging Multi-omics technologies Preclinical cardiometabolic animal models They will also gain professional development in data stewardship
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the goal to design combinatorial therapeutic approaches. The project will involve the use of genetically complex organoid-derived transplantation mouse models of pancreatic cancer, novel genetically
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on cell viability and DDR activation in established human cell models. The student will perform CRISPR screens to determine factors that affect resistance/sensitivity and follow these up with mechanistic
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dynamics and tissue morphogenesis during embryo development using cellular, molecular and mechanical approaches. Cell movements underlie tissue patterns and shapes. Using chick embryos as the model system
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communication skills with the ability to work collaboratively. Ideally, the candidate will have a strong background in molecular biology and/or biochemistry. A good knowledge of genomics and the chemistry
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learning and AI models to imaging data [3]. The student will be tasked with the development of new models for the early detection of CIN cancers, applying bleeding edge computational methods and machine
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Fixed-term: The funds for this post are available for 1 year. Applications are invited for a Research Associate (Postdoc) to join the Prorok Lab in the Department of Computer Science and Technology
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of Cambridge Department of Medicine Molecular Immunity Unit, housed within the MRC Laboratory of Molecular Biology. Shortlisted candidates will be invited to visit the institute to deliver a seminar and
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mouse models and immunology expertise (CRUK-CI), access to relevant patient material (matched fresh-frozen PDAC and serum samples). We will utilize AstraZeneca expertise in spatial and circulatory