-
are conserved across species, including in the mouse, making the aged mouse model a useful means to understand and identify the molecular mechanisms that drive this process (doi: 10.1038/s41586-024-07238-x
-
PhD Studentship - EASTBIO - The Impact of Diet-microbiome-immune Interactions on Intestinal Function
of dietary fats, once digested by gut commensal bacteria, can either directly stimulate host cells or act as procurers for the generation of small molecular lipid mediators such as prostaglandins (PGs). PGs
-
developmental incompetence and importantly, fertilised mutant oocytes generate abnormal single-pronucleus zygotes, a phenotype we recently showed is likely conserved in human. Thus, our animal model provides
-
work is linking microscopic (discrete) mechanics to macroscopic (continuum) models of active slender systems. The project involves three main components: Theoretical continuum modelling. Extend classical
-
our capacity to dissect contact-dependent communication. Synthetic biology approaches, such as the engineered synNotch system, have been successfully applied in models including mouse and fly. Zebrafish
-
understanding of the impact of these signals on lymphocyte function in healthy immune responses is currently limited. We have shown using in vitro models with healthy human donor cells that noradrenaline
-
dynamic environments, utilising Vision, Language, and Action (VLA) models. The candidate will focus on designing novel training regimes and/or novel architectures for learning in embodied environments
-
. Setting-up enzymatic reactions between sub-compartments to model and understand eukaryotic cellular metabolism. Developing new microfluidic tools to construct multi-compartment synthetic cells for drug