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tumours and metastases with the goal to design combinatorial therapeutic approaches. The project will involve the use of genetically complex organoid-derived transplantation mouse models of pancreatic
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on cell viability and DDR activation in established human cell models. The student will perform CRISPR screens to determine factors that affect resistance/sensitivity and follow these up with mechanistic
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Description DC6: Molecular and tissue determinants of adverse tissue outcomes in hearing implants. Join the prestigious Marie Skłodowska-Curie Actions (MSCA) Doctoral Network SHIELD (Strategies for Healing
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. molecular biology, genetics, virology) with substantial relevant laboratory experience. • Strong experience in molecular biology techniques, including nucleic acid extraction, nucleic acid sequencing (NGS
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cells or the tumor microenvironment reduces tumor growth and extends survival in preclinical models, underscoring their potential as dual-function therapeutic targets. To address this, we aim to develop
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at the point of commencing this post, with experience in contemporary molecular cell biology, tumour metabolism, experimental modelling and bioinformatics as applied to translational cancer genomics, ideally
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, with experience in contemporary molecular cell biology, tumour metabolism, experimental modelling and bioinformatics as applied to translational cancer genomics, ideally within the context of childhood
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coalitions for delivering reliable, low-carbon energy services. Collaborating closely with UK Power Networks, SSE Energy Solutions, and the University of East London, you will develop robust economic Model
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for an individual with a keen interest in cell biology to investigate the molecular mechanisms of Wnt signal transduction pathways and how these are disrupted in disease. The successful candidate will receive expert
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dynamics and tissue morphogenesis during embryo development using cellular, molecular and mechanical approaches. Cell movements underlie tissue patterns and shapes. Using chick embryos as the model system