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). Design and fabricate patterned surfaces optimised for enzyme immobilisation. Assess synergistic antibiofilm efficacy under static and dynamic (flow-based) biofilm models. Apply advanced microscopy, protein
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their targets are simulated at the atomistic level. The most widely-used tool for this are molecular mechanics force fields, such as those developed by the Open Force Field Initiative [https://doi.org
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are expected to provide insights into the fundamental dynamics of molecule-plasmon coupling and contribute to the development of molecular quantum light sources, paving the way for advancements in nanoscale
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molecular techniques (e.g. qPCR, metabarcoding) to characterise pathogen life cycles, host responses and environmental tolerances. Fieldwork will be conducted at selected coastal sites to assess natural
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research will be the inclusion stochastic elements in the simulations with the goal of minimising manufacturing variability and defect generation, i.e. robust manufacturing. The outputs of the work will
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ecosystems, particularly intertidal and shallow subtidal zones, are highly dynamic and thermally extreme, exposing organisms to both marine (MHW) and atmospheric (AHW) heatwaves, often in rapid succession
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the tropics, with for example recent analyses attributing extreme rainfall events and flooding in India moisture imported by atmospheric rivers (e.g. Mahto et al. 2023). So far, the dynamical drivers
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at the molecular scale, even breaking covalent bonds. Indeed, mechanical force is a formidable source of energy that, with its ability to distort, bend and stretch chemical bonds, is unique in its ability to promote
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, the project will develop algorithms for ecological sensing, adaptive motion planning, and energy optimisation under real-world constraints. Scaled experiments and high-fidelity simulations will validate system
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central question in evolutionary biology and has profound implications for predicting host–pathogen dynamics in changing environments and biodiversity conservation. In this project, you will investigate