-
Jochen Blumberger at the Condensed Matter and Materials Physics Laboratory, University College London, UK. Interested candidates may want to work on one of the following two projects. Project 1
-
challenge in modern medicine: many promising drugs lack effective delivery systems. Hence, this project not only allows the student to make a real-world impact, but also provides, through our strong network
-
their pandemic potential and classification as bioweapons. This project aims to develop a machine learning-accelerated NMR platform for the discovery of high-affinity inhibitors targeting viral RNAPs. Building
-
the synergistic effects of monoclonal antibodies and colistin. Building on extensive preliminary data, the project aims to uncover the mechanisms behind this synergy using advanced biophysical and molecular
-
production and capable of suppressing AMR gene dissemination in clinical and environmental settings. Approach and Methods: Synthetic biology: Construct modular conjugative plasmids with engineered payloads
-
) alter resistance mechanisms. Use high-throughput screening and biofilm models to identify conditions that reduce multidrug resistance (MDR). Build a systems-level understanding of how these mechanisms
-
for scientific publishing, international conference presentations, and professional development through the supervisors’ extensive networks in academia and industry. Research Environment: The project is hosted
-
leveraging acoustic streaming and cavitation effects induced by ultrasound, the system will enhance drug transport and biofilm disruption. This interdisciplinary project builds on prior EPSRC-funded research
-
PhD Studentship: Nanopore Technology for Rapid and Accurate Measurement of Antibiotic Concentrations
biotechnology, large-scale DNA sequencing, and directed evolution. Together, the labs provide a dynamic and supportive environment for interdisciplinary research at the interface of physics, biology, and
-
that suppress resistance gene transfer. Combining biophysics, microbiology, and materials science, the project will generate insights into how physical environments can be harnessed to control AMR. Approach and