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of this research is forensic proteomics. Specifically, this project aims to build a comprehensive and in-depth keratin (e.g., skin/hair) peptide mass spectral library for human identification using genetically
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NIST only participates in the February and August reviews. Methylation of CpG sites is an epigenetic modification and plays critical roles in many biological processes, including genomic imprinting
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DeCost brian.decost@nist.gov 301.975.5160 Description Trustability and physical interpretability are critical requirements for the development of robust and sustainable machine learning systems needed
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301.538.9058 Description Generation, control and detection of optical radiation either spectrally, temporally, or spatially is fundamental to optical technologies. Developing a versatile, manufacturable, and
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5235 Description Corrosion is estimated to cost $2.5 trillion dollars annually, of which ~$500 billion could be saved by the application of existing technologies. But for the remaining $2 trillion, a
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the objective of commercialization for AST [5]. Research supporting this application and others is now transitioning back to NIST in collaboration with the Molecular Cellular and Developmental Biology Department
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NIST only participates in the February and August reviews. Localization of proteins to bilayer lipid membranes (BLMs) is a complex but fundamental cellular process. The mechanism of binding varies
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interested in developing analytical strategies for the characterization of metabolic profiles of microbial communities, identification of unknown metabolites, and development of reference materials, all based
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spectrometry instrumentation has been pushed to the limits of mass detection to spectral resolutions over 100,000, allowing for specific mass determination and unknown compound identification. Analytical methods
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. This platform is not limited in dynamic range and thus will enable identification of the composition of complete proteomes through the individual sequencing of billions of peptides, including those of low