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systems design and fabrication Advanced microscopy skills (fluorescence, confocal, live-cell imaging) Molecular biology techniques, including: Gene expression analysis (qRT-PCR) Protein analysis (Western
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, uncovering novel cellular mechanisms. We employ state-of-the-art techniques in fly neurogenetics, proteomics, molecular biology, RNA biology, multi-omics, and quantitative imaging to investigate circadian
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metabolism, clinical sample analysis and clinical pharmacokinetics, and mass spectrometry imaging of small molecules, endogenous metabolites, lipids, proteins on tissue sections. What You'll Do LC MS
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responses using imaging and electrophysiology. Multi-channel stimulation optimization will be achieved using a closed-loop, semi-automated experimental paradigm. The findings from these experiments will feed
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, subcutaneous, intraperitoneal, and intra-cardiac injections of cells to generate tumor models, bioluminescence Imaging, and animal necropsy. Other wet-lab techniques or assays maybe involved depending on how
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/reloading models for studying musculoskeletal adaptation Experience in mouse dissections and surgery Prior work in animal/tissue imaging, including microcomputed tomography analysis, as well as histological
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new skills in biochemistry and molecular and cellular biology, including fluorescence microscopy, live-cell imaging, ratiometric calcium imaging, transcriptomics, proteomics, mammalian cell culture
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over 56,000 square foot of dedicated, state-of-the-art facilities. BI provides some of the most diverse research environments at U-M. Many grad students, postdocs, visiting scholars from various
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plasticity. We study questions at a variety of levels, Ranging from synaptic and cellular studies using patch-clamp electrophysiology, large-scale population recordings using 2-photon Ca2+ imaging in awake
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-the-loop simulations, prototype development, and bench-level testing to validate design concepts and control implementations. Review and analyze relevant literature, industry standards, and emerging