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in animal models. A Ph.D. in Pharmacology, Biochemistry, Molecular Biology, Cell Biology or Physiology, and knowledge and experience with molecular methods is required. Experience in cardiovascular
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on understanding the molecular mechanisms underlying aortic aneurysm and valve disease. Utilizing a variety of approaches including stem cell biology, gene editing, bioengineered human vascular grafts and animal
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experiments to validate findings from the omic studies. The desired skill set is split between dry lab (bioinformatics) and wet lab (basic science/animal models). Additionally, the individual will be required
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field Willingness and demonstrated track record of working on collaborative teams within and outside the laboratory Experience and willingness to work with small animals (e.g., mice) Willingness to learn
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, subcutaneous, intraperitoneal, and intra-cardiac injections of cells to generate tumor models, bioluminescence Imaging, and animal necropsy. Other wet-lab techniques or assays maybe involved depending on how
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molecular analyses to animal models to human applications. More information about the Kaczorowski lab can be found at http://kaczorowski.lab.medicine.umich.edu Mission Statement Michigan Medicine improves
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interdisciplinary lab focuses on investigating genetic and epigenetic changes in traumatic brain injury. The successful candidate will work on animal models of brain injuries and apply cutting-edge spatial multi-omic
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human brain tissue to determine radiotracer binding affinity, selectivity, and tissue distribution. Perform in vivo PET imaging studies in small animal models (e.g., rodents/nonhuman primates) to evaluate
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, including but not limited to Cloning, DNA/RNA extractions, PCR, western blotting, ELISA; performing purification of secreted proteins; maintenance of mammalian cell cultures; animal handling; and basic