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the interface of the expertise of the De Wit lab (molecular mechanisms of synaptic connectivity) and the Holtmaat lab (synaptic integration of sensory input and context in cortical circuits). The project will
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. The Verstreken lab is developing advanced multielectrode array systems to mimic human brain circuits relevant to Parkinson’s disease, and has been supported by the ERC for the past 15 years. The Gonçalves lab is
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center for artificial intelligence in life sciences, we benefit from high-throughput computing infrastructure to support advanced data analysis and integration. Profile We are looking for a motivated
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optimization and validation and in addition, we aim to discover novel VHHs capable of crossing the blood-CSF barrier and delivering therapeutic cargoes to the brain. You will become an integral member of a
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driving context-specific expression. You will work very closely together with your wet-lab colleagues for the design and follow-up of experimental validations. PhD (or MSc with research experience) in AI
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for the design of synthetic promoters and data analysis. PhD in (Plant) Biotechnology, Molecular Biology, Biochemistry or equivalent A publication record in peer-reviewed journals, and excellent proficiency in
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-ray videocystometry in awake mice, and optogenetic modulation of urothelial cells. The candidate will design and conduct experiments exploring mechanosensitive ion channels (e.g. TRPV4, PIEZO1/2) and
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. The Brassinosteroid group (https://www.russinovalab.be) studies the function of brassinosteroid hormones in stomatal development, focusing on mechanisms of signal integration between brassinosteroid and stomatal
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-generation combinatorial editing tools and applying them to study genetic interactions. As all our projects integrate high-throughput experiments with computational analyses we are particularly interested in
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including fragmentomics, methylomics, etc). In addition, results will be compared and integrated with bulk and single-cell/spatial data obtained on matching tumor cells. About TOBI-lab The overarching goal