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the mechanisms of neurovascular coupling (NVC) in the human retina — a key physiological process whose early dysfunction is linked to Alzheimer's disease. The team has developed a new cellular-resolution imaging
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coupled neuronal and vascular dynamics of the human retina. Scientific Objective The goal of this PhD project is to develop new optical methods and advanced image-processing approaches to simultaneously
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vivo experiments to investigate retinal neurovascular dynamics using the AO-RSO system; Developing or adapting high-speed image acquisition and processing methods for the simultaneous extraction
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expertise in plant sciences, optical technologies, and data processing. The existing imaging Mueller polarimeter, which is sensitive to the microstructural properties of biological tissues, will serve as the
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and numerically predicting the infiltration of the final matrix by CVI. To this end, X-ray tomography acquisitions will be performed; the images will then be analyzed and processed to produce (i
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Eligibility criteria PhD in Applied Physics, Optics, Biomedical Imaging, or a related field; Strong expertise in experimental optics and optical instrumentation; Proficiency in image processing and data
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the Quantitative Imaging Platform of Villefranche (PIQv; https://sites.google.com/view/piqv ), which oversees the operation of the tools that the team develops. Those tools include imaging sensors, such as the
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the European framework) Know-how: Confirmed experience in stereotaxic surgery in mice Practice of behavioral analyses Ability to develop data analysis scripts Ability to design, prototype and integrate
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explainable. Our team builds upon over 20 years of expertise in image processing algorithm research and more than 15 years of experience in developing open-source software for image processing and digital art
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on apical pulling forces. Meanwhile, Jacques Pecreaux Lab has investigated the forces positioning the spindle in the C. elegans zygote, through an approach combining image processing, modelling and