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are three-stranded nucleic acid structures consisting of an RNA-DNA hybrid and a displaced single-stranded DNA (Allison et al., CST 3, 38-46 (2019)). They form naturally during transcription, where
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PhD position in biomimetic DNA origami mechanisms Faculty: Faculty of Science Department: Department of Chemistry Hours per week: 36 to 40 Application deadline: 15 August 2025 Apply now
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Description We are seeking a motivated PhD candidate for a PhD thesis in bioorganic chemistry, focusing on the chemical synthesis of multi-fluorescence labelled DNA and PNA conjugates, conjugation
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in its capacity to resolve nanometer small conformational changes within single biomolecules (proteins, DNA, RNA), without suffering from ensemble averaging. Its Achilles heel is, however, photo
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. Enhancers, DNA elements with binding sites for transcription factors, play a key role in this process. Recently, it has become clear that enhancer activity requires the formation of sub-micrometer-sized
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function, with a particular emphasis on DNA/RNA-LNPs for next-generation gene therapeutics. Your tasks This PhD position is part of a larger EU-funded project focused on the metrological characterization
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100%, 3 years) on DNA data storage. The Machine Learning and Information Processing group at TUM works in the intersection of machine learning and signal/information processing with a current focus on
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Job Description AI has begun to transform molecular discovery and design for proteins, DNA, RNA, small molecules and more. Yet many outstanding challenges in health and sustainability remain data
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of DNA barcoding for improving identification of modern and fossil chironomid larvae. This PhD project will contribute to further developing fossil chironomid research by exploring one or several
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PhD candidate in Design and synthesis of pyrophosphate mimetics to study enzymes involved in natural
Apply now PhD Candidate in the Design and Synthesis of Pyrophosphate Mimetics to Study Enzymes Involved in Natural ADP-Ribosylation The Faculty of Science Leiden and Leiden Institute of Chemistry