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Correct gene transcription by RNA polymerase II to generate new RNA molecules is crucial for proper cell function. However, transcription by RNA polymerases can be blocked by DNA damage on the DNA
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for proper cell function. However, transcription by RNA polymerases can be blocked by DNA damage on the DNA template, for example by UV-light or other chemicals. Transcription-blocking DNA damage can therefore
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Genome maintenance pathways are crucial to preventing genetic diseases such as cancer. Major progress has been made in our understanding how DNA damage is repaired. Yet, even in the absence
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. Major progress has been made in our understanding how DNA damage is repaired. Yet, even in the absence of damage, DNA itself can adopt unusual conformations that threaten the integrity of the genome
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Profile First Stage Researcher (R1) Positions PhD Positions Country Netherlands Application Deadline 1 Feb 2026 - 15:00 (Europe/Amsterdam) Type of Contract Temporary Job Status Full-time Hours Per Week 40
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funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description PhD student for studying in
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PhD student for studying in vitro single-molecule transport across peroxisome mimics Job requirements The selective control of import and export across membrane-spanning pores is vital for our cells
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PhD candidate in Design and synthesis of pyrophosphate mimetics to study enzymes involved in natural
Apply now PhD Candidate in the Design and Synthesis of Pyrophosphate Mimetics to Study Enzymes Involved in Natural ADP-Ribosylation The Faculty of Science Leiden and Leiden Institute of Chemistry
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technology, which works by cutting a DNA sequence at a specific genome location and deleting or inserting genes there. The CRISPR-Cas method provides an excellent basis for the development of unprecedented
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We are looking for a PhD candidates for a joint project between the groups of prof. Nathalie Katsonis, prof. Willem Kegel, and prof. Ben Feringa, that will be carried out within the framework