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regions (UL-CDRs) represent a unique structural class with exceptional potential for targeting otherwise inaccessible epitopes. These UL-CDRs feature a distinctive architecture comprising a β-ribbon stalk
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annually, with life-threatening consequences for immunocompromised individuals. With few antifungal drugs available and resistance on the rise, this project explores a novel strategy: engineering the fungal
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PhD Studentship: Nanopore Technology for Rapid and Accurate Measurement of Antibiotic Concentrations
samples. Nanopore technology, which detects molecules via changes in ionic current as they pass through nanometer-scale pores, has revolutionised nucleic acid sequencing and holds untapped potential
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rather than the structured biofilms found in real-world environments. This project investigates how engineered surface topographies influence HGT dynamics, aiming to develop design principles for materials
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The UCL EPSRC Landscape Award (UELA) is recruiting 50 fully funded, 4-year PhD studentships. You can apply for any of the projects offered through the UELA project catalogue (over 100 projects
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library of polymer candidates with varied physicochemical properties (charge, size, structure, biodegradability) Formulate polymer–mRNA nanoparticles and characterise their size, stability, and mucus
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on recent advances in recombinant RNAP production, cryo-EM structural elucidation, and fragment-based screening, the project will integrate fluorine-based NMR spectroscopy with active learning algorithms and
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Supervisors: Prof Manish Tiwari Prof Shervanthi Homer-Vanniasinkam Clinical Partner: The Royal National Orthopaedic Hospital (RNOH) Collaborator: Dr. Priya Mandal – UCL Mechanical Engineering
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(SONATA, EP/V028626/1) and brings together expertise in microfluidics, fluid dynamics, nanoparticle engineering, and dental microbiology. Approach and Methods: Engineer in vitro models of bacterial biofilm
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will uncover the interfacial solvation structure, validated through comparison between computed and experimental sum-frequency vibrational spectroscopies, as well as the mechanism of chemical