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fibrosis; transcriptomic and imaging approaches (RNA-seq), high-content imaging (ImageStream), and metabolic profiling (Seahorse); recombinant protein engineering; structural biology techniques: X-ray
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4 Oct 2025 Job Information Organisation/Company CNRS Department Laboratoire de Mécanique et Génie Civil Research Field Engineering » Materials engineering Physics » Acoustics Researcher Profile
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Information Eligibility criteria 1. Fundamental knowledge • PhD in virology, molecular biology, or structural biology. • Strong knowledge of structural biology and protein–protein interaction methods. • Mastery
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activity (2, 3). This finding was unexpected because PCPE1 and PCPE2 are very similar in terms of sequences and structures. Objectives The main objectives of the PhD project will be (i) to elucidate
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that will bring us closer to the cellular context. The PhD student will use a combination of biochemical and structural biology methods: reconstitution of ribonucleoprotein complexes from cell extracts and/or
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of the facilities required to develop this PhD project: bacterial culture, rheology, surface charge measurements (zeta potential), thermal analysis, X-ray diffraction (XRD), infrared spectroscopy, mechanical behavior
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. Molecular biology (plasmid construction, gene inactivation, etc.) High-density bacterial culture in bioreactors Protein expression and purification Characterization of glycoproteins using a range of