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propagate through bacterial communities while deactivating AMR genes. However, current designs are limited by scalability and complexity. This project aims to overcome these limitations by integrating large
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regions (UL-CDRs) represent a unique structural class with exceptional potential for targeting otherwise inaccessible epitopes. These UL-CDRs feature a distinctive architecture comprising a β-ribbon stalk
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disinfectants. With antimicrobial resistance (AMR) on the rise, there is an urgent need for non-antibiotic strategies to prevent and control biofilm formation on medical devices. This PhD project proposes a novel
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prevalent noncommunicable disease globally. The confined and complex architecture of the oral cavity, particularly in regions such as dentinal tubules and root canals, makes effective antimicrobial treatment
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healthcare settings. Approach and Methods: Synthesize gold nanostars with optimised optical and surface properties for enhanced plasmonic signal amplification Engineer LFA architectures incorporating salt
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-penetrating capabilities Evaluate delivery efficiency in cell-based models mimicking lung and immune tissues Identify structure–function relationships to inform rational design of future mucosal delivery
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nanoparticles can protect them and help deliver them precisely where they are needed. However, designing suitable AMP-nanoparticle combinations is complicated. Many formulation ingredients, concentration ratios
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PhD Studentship: Nanopore Technology for Rapid and Accurate Measurement of Antibiotic Concentrations
the environment and the lack of routine monitoring tools. Current methods for measuring antibiotic concentrations, such as HPLC and mass spectrometry, are expensive and require complex instrumentation, limiting
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chemistry and nanoscale structure, these coatings will offer long-term, biocompatible protection against infection. The project will involve materials design, fabrication, characterisation, and biological
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guidelines for the design of improved organic materials. Interested candidates may want to take a look at our recent work: https://www.nature.com/articles/s41467-022-30308-5 & https://www.science.org/doi