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sequence swapping between PCPE1 and PCPE2 to identify the important residues for PCPE2 inhibitory function (molecular biology, activity assays, surface plasmon resonance). In parallel, we will try to solve
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one species. Secondly, they will explore the evolution of this molecular complex (or single nuclease) across nematode species to understand its origin. In parallel, they will analyse the dynamics
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-CE50-4784 ). In parallel, we will maintain our long-standing collaboration with our local partner (A. Klymchenko, Pharmacy Faculty, Strasbourg), expert at synthesizing LH polymer materials from
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encapsidation. In parallel, the Nano-DMS-MaP method will be used to assess the impact of m6A on RNA structure. In a second part, the PhD student will study the impact of HIV-1 infection on the host cell's
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, the PEPR FORESTT is funding half of the thesis (funding already secured), as well as the full cost of missions and analysis fees. It is being carried out in parallel with another proposed thesis