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information is very important for many applications relying on non-equilibrium processes, such as light triggered chemical reaction to synthesize novel materials, the pH triggered drug release, electric field
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reproducibility for isolating and purifying EVs from a representative biological model. Measurements should incorporate the use of process controls, rigorous statistical analysis techniques and method robustness
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975 8997 Description Metabolomics can provide insight into many cellular processes. Metabolomic profiles of biological fluids (plasma/serum, urine, etc.) or bioprocess samples (mammalian cell lines
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process via cell banks, raw materials, or the environment. These adventitious agents can potentially cause harm to recipients. Current testing methods are very time consuming and may not detect all types
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processes of the organism at a given time and enables a characterization of the range of health parameters one would expect in changing environments. By probing the health status of a myriad of species, we
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system. A third, variable temperature STM system is included in this facility for examination of processed samples and AFM-type measurements, such as scanning gate microscpy. Work is carried out within
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NIST only participates in the February and August reviews. Localization of proteins to bilayer lipid membranes (BLMs) is a complex but fundamental cellular process. The mechanism of binding varies
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controls the interactions of and between nanotubes dispersed for processing in liquid media. A key example of this is that liquid phase separation techniques rely on modulating these interactions using
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less). To address this technological bottleneck, we are developing a new technology platform--next gen protein sequencing--based on large-scale, massively parallel, single-molecule peptide sequencing
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molecular motors and RNA-folding. In a parallel effort, we significantly enhanced the biophysical capabilities of an atomic force microscope (AFM). Specifically, we achieved sub-pN force precision and