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, Engineering) and should be self-motivated, able to take ownership of their research, and effectively communicate their research findings. Training in all the computational and experimental methods will be
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the computational and experimental methods will be provided in the projects, although relevant previous experience would be advantageous. Applications for this PhD project should be submitted via the University
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and inverse agonism and provides an exciting opportunity to use structural biology and biophysics methods to investigate fundamental aspects of how these receptors work. The structural and biophysical
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chromatin profiling methods along with CRISPR/Cas9-meduated cell line engineering and various animal models. You will study the effects of the activation or depletion of chromatin-modifying enzymes using
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relevant PhD (or nearing completion) or possess an equivalent qualification/experience in a related field of study and be able to demonstrate sufficient knowledge in the discipline and of research methods
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the proteins associated with their binding sites with a view to understanding therapeutic mechanisms [e.g. see Nature Biotechnology 2023, 41 1265]. We are expanding this work to create methods to characterise
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situ, with direct structure determination, and (ii) investigating and optimizing methods for chirality determination using electron crystallography. Candidate We are looking for a highly motivated and
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microbiology or Biomedical Sciences or related discipline and be able to demonstrate sufficient knowledge in the discipline and of research methods and techniques to work within established research programmes
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. Current Mass Spectrometry approaches have been unable to assess most of the FOXA1 protein for PMTs, but new Mass Spectrometry methods such as 'top-down' approaches permit an unprecedented opportunity
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The Centre for Doctoral Training in Nanoscience and Nanotechnology (NanoDTC) at the University of Cambridge invites applications for its 3.5-year interdisciplinary PhD programme. The programme