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) are important mediators of most cellular processes. Understanding how proteins interact with each other, ideally at structural resolution, is key in understanding molecular processes, how disease mutations would
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, to how epigenetics regulates cellular identity or neural memory. Activities and responsibilities The research group of Petra Beli offers the following PhD project: R-loops are secondary DNA structures
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model systems zebrafish and fruit fly, and structural biology (including AlphaFold predictions and cryo-EM), we will dissect the roles of these novel mRNA export regulators and define how they interface
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highly enriched heterochromatin structure blocks the accessibility of homologous recombination (HR) repair machinery. This project will investigate how DNA damage in sperm alters the epigenome