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see the following publications: CTCF/RAD21 organize the ground state of chromatin-nuclear speckle association. Nature Structural & Molecular Biology. ISSN 1545-9993 Nuclear speckles regulate functional
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of nuclear structure and function. Current Opinion in Cell Biology 26, 10-18. Hazra, R., Brine, L., Garcia, L., Benz, B., Chirathivat, N., Shen, M.M., Wilkinson, J.E., Lyons, S.K., and Spector, D.L. 2022
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behaviors. Genes that determine such behavioral differences, for example between the singing mouse and the lab mouse, must act via neural circuits within the brain. Yet, the structural and functional changes
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autoimmunity triggered by cancer. We employ a multidisciplinary approach, integrating structural biology, high-resolution imaging, and electrophysiology. While expertise in cryo-electron tomography (cryo-ET