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human stem cells for in vitro modeling of neurodegeneration disease. Projects in the lab are at the interface of systems biology and bio-medical research. In particular, we aim at developing novel
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, advanced co-culture organoid assays, and in vivo models to decode the mechanisms underlying CAF-driven CRC evolution. Access to single cell RNA sequencing and spatial transcriptomics data from active
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vivo cancer models. The candidate will be expected to: Determine the effects of the identified VFs using various in vitro and in vivo assays and investigate the underlying mechanisms Contribute
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BioEngineering Experience with fluidics devices, 3D printed devices, 3D cell culture models and bioinformatics/computational biology (e.g., R, Python) is an asset Team player Proficient knowledge in English is
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analyzing whole organism models (zebrafish and mouse) to dissect the pathophysiology of a recently identified rare pediatric neurometabolic disorder. The approach involves mainly deep longitudinal phenotyping
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health and translational medicine using a "bench-to-bedside" approach. By harmonising and analysing diverse biomedical data, while focusing on the secure data processing and predictive modelling, we aim